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PEP after a possible exposure

PEP is emergency medicine that may prevent HIV after a possible exposure.

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What to know

  • PEP must be started within 72 hours; the sooner it is started, the better.
  • PEP is for emergencies, not regular prevention.
  • A health care provider can assess the exposure and, when appropriate, prescribe a 28-day course.

This KISSYN summary is educational, not medical advice. Guidance, availability, and eligibility can change; talk with a qualified health care provider about your situation.

Open the official CDC source

KISSYN review: August 31, 2026 · Reverify by November 30, 2026